Content Author:
Dr Mark Fowler
Level:
Undergraduate bioscience or medical student.
OER Features:
SCOOTER109a_Deoxyhaemoglobin PPT
SCOOTER109b_Deoxyhaemoglobin PDF
SCOOTER110a_DeoxyhaemoglobinS PPT
SCOOTER110b_Deoxyhaemoglobin S PDF
OER Description:
Here are some deoxyhaemoglobin molecules constructed using Jmol – an open-source Java viewer for 3D chemical structures. You can access Jmol here:
The images here are of deoxyhaemoglobin versus deoxyhaemoglobin S, and you can see how a simple genetic mutation can cause an alteration in molecular structure. It is this transformation that causes the development of sickle cell disease.